We have had a lot of activity in recent months on the OpenTox project with regards to developing a linked data and resource infrastructure for the support of interdisciplinary predictive toxicology research and safety assessment. I enclose several links below including our recent overview workshop presentation in Potsdam, reports, demonstrations, technical links and interest groups. A paper will be published as an Open Access publication in coming weeks (reference below).
We welcome your joining this community and movement to work towards the common goal of safer products and a safer environment, supported by new alternative and advanced methods.
Your Resources If you have a useful resource you would like to see integrated into OpenTox, e.g., a database from your project to which an OpenTox web service could be added, please contact me to discuss.
OpenTox Demos (Please keep in mind these are early prototype applications and may not have features you want. We welcome requests from you for what you additionally need in these applications or others.) http://www.opentox.org/toxicity-prediction
Publication Reference Collaborative Development of Predictive Toxicology Applications, B. Hardy, N. Douglas, C. Helma, M. Rautenberg, N. Jeliazkova, V. Jeliazkov, I. Nikolova, R. Benigni, O. Tcheremenskaia, S. Kramer, T. Girschick, F. Buchwald, J. Wicker, A. Karwath, M. Gütlein, A. Maunz, H. Sarimveis, G. Melagraki, A. Afantitis, P. Sopasakis, D. Gallagher, V. Poroikov, D. Filimonov, A. Zakharov, A. Lagunin, T. Gloriozova, S. Novikov, N. Skvortsova, D. Druzhilovsky , S. Chawla, I. Ghosh, S. Ray, H. Patel, S. Escher, accepted 3 June 2010 for Open Access publication in J. Chemical Informatics http://www.jcheminf.com/ (2010).
For those of you in the community interested in closer involvement with OpenTox development and application use cases, joining related new initiatives and proposals, discussing our collaborating more closely with your own project, taking a leadership role etc., please feel free to contact me with your interests and motivations, and we could for example have a chat via Skype, get introduced and discuss your needs or ideas.
Contact Barry Hardy in his role as OpenTox Coordinator at Barry.Hardy !-(at)-* douglasconnect.com
When I started the eCheminfo community of practice in late 2003 we focused initially on using the approach of virtual conferencing and communications to get the community started. More recently I have given more attention to developing face-to-face conference and workshop activity and initiating collaborative research. While on this journey it has been personally rewarding to have met and made contact with hundreds of scientists in the international community and to additionally be involved in supporting their networking, career development and research in drug design, discovery and modelling. It has also been rewarding to have just met so many great people and to have had the chance to interact with them, be it on a computer, in a workshop exercise, or on a punt trying to get down the river as we usually do when we are in Oxford. So far we seem to be better on computer-based physics than boat physics!
And so I have come full circle and can see the need to prioritise the virtual community aspects of eCheminfo further again, to support the continuation of all these worthwhile interactions in the community. So LinkedIn is one place to start. I have been on there for some years and we have had a group area, but have not really done much with it. It has primarily been useful for some introductions between people. However recent feature additions for discussion, posting of news, job announcements etc. have been added, so it seems worthwhile to try using it more for supporting continuing interactions in the community. So I am initiating today invitations to the eCheminfo community to join us there for discussion, news and networking on what is happening in the world of drug discovery informatics, cheminformatics, bioinformatics, etc. Use of the group is intended for scientific and professional exchange purposes only. As included in our mission we encourage cross-disciplinary cross-sector participation so from medicinal chemists in the pharmaceutical industry through toxicologists in government institutes through PhD students working on their modelling research problems are welcome!
To request joining the eCheminfo LinkedIn group please follow the following link and introduce yourself with a group joining request: