The Ferryman

Knowledge Management Training, 6-10 May 2013

We will run our international Knowledge Management Training week again in Switzerland 6-10 May 2013.

Topics: 
Knowledge Management (KM) Concepts, KM Practices, Business Case, Strategy, Program Planning, KM Frameworks, KM & Organisational Culture & Development, Change Management for KM Programs, Leadership and Competencies for KM Knowledge Assessment, Metrics, Enterprise Knowledge Management, Process-oriented Knowledge Management, Knowledge Mapping, Benchmarking, Expertise Location, Search, Personal Knowledge Management, Web 2.0, Communities, Collaboration 

More Information: 
http://douglasconnect.com/km/km-training
http://douglasconnect.com/events/Basel2013

Program Brochure (pdf): 
http://douglasconnect.com/sites/default/files/KMTrainingBrochure-Swiss-Basel-2013.pdf

ToxBank Infrastructure - paper available in Open Access

The following publication is now available in Open Access:

The ToxBank Data Warehouse: Supporting the Replacement of In Vivo Repeated Dose Systemic Toxicity Testing

Pekka Kohonen, Emilio Benfenati, David Bower, Rebecca Ceder, Michael Crump, Kevin Cross, Roland C. Grafström, Lyn Healy, Christoph Helma, Nina Jeliazkova, Vedrin Jeliazkov, Silvia Maggioni, Scott Miller, Glenn Myatt, Michael Rautenberg, Glyn Stacey, Egon Willighagen, Jeff Wiseman, and Barry Hardy

Molecular Informatics
Special Issue: Advances in Computational Toxicology

Volume 32, Issue 1, pages 47–63, January 2013

http://onlinelibrary.wiley.com/doi/10.1002/minf.201200114/abstract

Crowdsourcing 10,000 Guts

Get a profile of your stomach bugs, and help drive data collection of new research project ...

... Nice looking crowdsourcing approach to quickly gather lots of data on the bugs in 10,000 stomaches:

http://www.genomeweb.com/team-gearing-gut-microbiome-crowdsourcing-project

A Shared Moment of Great Happiness

Barry Hardy and Spela Predan, Just Married.

 

OpenTox 2011 Technical Reports

The following #OpenTox 2011 technical reports in predictive toxicology are available for downloading:

OpenTox D1.4 Report on Evaluation of the Final Implementation

OpenTox D2.4 Report on Final Framework

OpenTox D3.4 Report on Final Database with Additional Content

OpenTox D4.3 Report on Final Version of (Q)SAR algorithms

OpenTox D5.3 Report on Validation Against Confidential Data

OpenTox D5.4 Report on Final Validation Routines with Facilities to Validate Against Confidential Data

ToxBank wiki open

I am happy to inform that we have now made the first version of the ToxBank wiki (wiki.toxbank.net) open.

The first version of this wiki contains information on reference compounds which will be used to probe mechanisms of toxicity as carried out by experiments and modelling under the SEURAT-1 predictive toxicolgy research program. The long term strategic target of this program is "Safety Evaluation Ultimately Replacing Animal Testing". We make this resource public to provide useful information in support of other research projects with similar goals and to foster cross-fertilisation, alignment and collaboration.

I will be happy to receive your feedback and suggestions on this new resource.

Barry Hardy

barry.hardy -!(at)- douglasconnect.com

https://www.facebook.com/barry.hardy3

Predictive Toxicology Ontology Perspectives and Roadmap

Re: #OpenTox, ontology, new predictive toxicology systems

The following papers are now available from the new issue of Altex:

Toxicology ontology perspectives
This article provides an overview of some of the leading developments in
incorporating ontology into new knowledge-based systems in predictive toxicology.

http://www.altex.ch/en/index.html?id=16&aid=3

A toxicology ontology roadmap
In this article we lay out the main justifications and needs for ontology
development to enable the building of interoperable predictive toxicology systems
and services for industry to design and test safer products.

http://www.altex.ch/en/index.html?id=16&aid=2

OpenTox Toxicology Ontology Development

This article is just out online describing initial #OpenTox ontology work:

#OpenTox predictive toxicology framework: toxicological ontology and semantic media wiki-based OpenToxipedia

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337268/

#OpenTox - #Bioclipse Cloud article

The final version of our first #OpenTox - #Bioclipse paper on getting our tox cloud working with the Bioclipse workbench for interactive design for safety purposes is now available in open access. See http://www.biomedcentral.com/1756-0500/4/487

Updated progress of Scientists Against Malaria initiative

I presented a progress update on our Scientists Against Malaria drug discovery initiative at the BIO-IT Europe conference in October. You can download the presentation as a pdf:

Collaborative Virtual Organisation and Infrastructure for Anti-Malarial Drug Design