I provide below a schedule for the upcoming InnovationWell and eCheminfo Community of Practice meetings at Bryn Mawr.
I also include a location map here which may be useful upon arrival:
Download bryn_mawr_campus_map_douglas_connect_meeting.pdf
[Please follow continuation here to view schedule.]
Current advances in computer-based predictive toxicology offer the potential to create more advanced environments for the screening and prediction of safety issues due to chemical and drug adverse side effects, drug-drug and chemical-system interactions, and chemical and drug toxicologies in the environment and the human body. Advances in this growing field also offer the potential to replace or reduce the need for animal testing and to reduce later stage clinical trial failures or new product development rejection. Acceleration of progress in practical applications requires the creation of interoperable environments, knowledge sharing, data integration, algorithm development, and extensive validation and testing.
Numerous opportunities exist in this field for scientific advances, but also for innovation, service and product development, and value creation. Additionally, significant collaboration approaches are a scientific, industry and society imperative to advance this field and the safety of new products and all society members. Collaborative approaches need to support the multidisciplinary networking and collaboration between computer scientists, biologists, chemists, toxicologists, product development and clinical and environmental researchers, and to network groups, centers, initiatives, projects and data into interoperable semantic frameworks, systems, knowledge bases and virtual organisations.
At our Predictive Toxicology session chaired by Artem Cherkasov (University of British Columbia) running 17 October 2008 at Bryn Mawr recent developments in the field of predictive toxicology will be presented and discussed.
The session will be preceded the evening of October 16 by a Knowledge Café to discuss Collaboration Opportunities in Predictive ADME & Predictive Toxicology.
A description of the session with presentation abstracts follows. Please add your comments, discussion or questions at the end of the post.
Predictive Toxicology
(Please follow continuation here to read abstracts. Comments can be made at the end.)
Healthcare is a highly complex, information-driven industry, and effective knowledge management is at the heart of the drug discovery and development process. Translational medicine is becoming increasingly important within the pharmaceutical industry where it is defined by a variety of initiatives designed to facilitate the transfer of knowledge from the bench to the bedside and back.
On the 15 October 2008 at the InnovationWell Community of Practice Meeting at Bryn Mawr College, Philadelphia, I will chair a day-long session where we have brought together a diverse set of speakers representing a broad spectrum of activities across the pharmaceutical workflow – from target identification to clinical trials. Each presentation will describe specific examples of advances in translational medicine brought about by practical approaches to improved knowledge management. Sometimes these advances will be technology-based, sometimes they will have resulted from innovative forms of collaboration and the use of Web 2.0 tools. Together we hope these speakers will stimulate discussion and the transfer of insights and ideas illustrating the potential of knowledge management tools and techniques to drive advances in translational medicine.
A description of the session with presentation abstracts follows:
Knowledge Management in Translational Medicine
http://innovationwell.net/COMTY_confprogr08kmtransmed
(Please follow continuation here to read abstracts. Comments can be made at the end.)
Continue reading "Knowledge Management in Translational Medicine" »
This year's InnovationWell Autumn Community of Practice Meeting will take place 14-17 October 2008 at Bryn Mawr College, Bryn Mawr, Philadelphia, USA to discuss the following areas of Innovation in Life Science & Healthcare R&D:
Critical Path Advances in Drug Development, Innovation & Knowledge Management in R&D and Translational Medicine, Computational Biology, Predictive ADME, Predictive Toxicology, Metabolomics, Biomarkers, Systems Biology
Program Summary
Systems Biology, chaired by Keith Elliston (Genstruct)
Computational Biology, chaired by Debraj Guhathakurta (Merck)
Knowledge Management in Translational Medicine, David Bousfield (Ganesha Associates)
Applications of Metabolomics to Drug Discovery & Development, chaired by Bruce Kristal (Brigham and Women's Hospital)
Predictive ADME, chaired by Anthony E. Klon (Pharmacopeia Drug Discovery)
Predictive Toxicology, chaired by Artem Cherkasov (University of British Columbia)
Pre-Conference Workshop, 13 October 2008
Knowledge Management in R&D
chaired by John Conway (Accelrys) and Frank Hollinger (FRESH Directions Consulting)
Speakers
Keith Elliston (Genstruct), Debraj GuhaThakurta (Rosetta Inpharmatics, Merck & Co.), Stephen W. Edwards (U.S. Environmental Protection Agency), Paul McDonagh (Gene Network Sciences), Christopher M.L.S. Bouton (Pfizer), James R. Brown (GlaxoSmithKline), John Wilbanks (Creative Commons), Barry Bunin (Collaborative Drug Discovery), Michael Liebman (Windber Research Institute), Jerry Wright (Johns Hopkins Medical Institutions), Anastasia Christianson (AstraZeneca), James Golden (Science Applications International Corporation), John Speakman (National Cancer Institute), William Hayes (Biogen Idec), Andrew McMurry (Harvard Medical School), Eugene Clark (Partners Healthcare), Alvin Berger (Metabolon), John Newman (USDA), Bruce Kristal (Brigham and Women's Hospital), Anton Hopfinger (University of New Mexico), Heidi Einolf (Novartis), Yojiro Sakiyama (Pfizer), Olga Obrezanova (BioFocus DPI, UK), Anthony E. Klon (Pharmacopeia), Artem Cherkasov (University of British Columbia, Canada), Ann Richards (US EPA), Curt Breneman (RPI), Alex Tropsha (UNC), Barry Hardy (Douglas Connect), Weida Tong (FDA)
CFP
We invite contributed papers from members of academic, government research and commercial organizations on areas of new research and innovation relevant to innovation and knowledge management in the life sciences. The work presented should involve innovative new method development or application in the areas of systems biology, translational medicine, knowledge management, computational biology, metabolomics, predictive ADME, predictive toxicology or bioinformatics. Studies including experimental work in medicinal chemistry, screening, experimental toxicology, pre-clinical evaluation, lead optimisation and translational medicine are welcome.
Abstracts (300-500 words) should be submitted to innovationwell -[at]-douglasconnect.com by 31 July 2008, and be accompanied by a short biography of the presenting author (300-500 words). Abstracts approved by the scientific organizing committee will be selected for scheduling on the conference program and in meeting poster sessions. Authors will be notified of acceptance as soon as a review of submitted materials takes place and at the latest by 15 August 2008.
Bursary
Bursary Awards will be used to support the attendance of a selection of academic young investigators at the meeting and workshops. Applicants should be working in a relevant area of research related to life science, healthcare, and drug product discovery and development at the postdoctoral, graduate student and senior undergraduate levels.
To apply for the bursary please send an email with a) your abstract and biography (300-500 words each), b) your CV of 1-2 pages, c) a short description of your interests and career motivations related to R&D (300-500 words) to innovationwell -[at]- douglasconnect.com by 31 July 2008. The recipients of the bursary awards will be selected based on an evaluation of the quality and innovation of the described research and the potential positive impact of attendance at the meeting on their research and career progress. Authors will be notified of acceptance by 15 August 2008.
Poster Session
All InterAction Meeting registrants are eligible to present a Conference Poster. The Poster Sessions will take place in the evenings in Thomas Great Hall on campus, where refreshments and dinner are also served. Poster Abstracts (300-500 words) with Title, Institution, Authors and Contact Information should be submitted to barry.hardy -[at]-
douglasconnect.com Abstracts will be considered based on date of submission and quality, and will be reviewed and accepted as they are received. To be considered for the formal program, they should be submitted at the very latest by 31 August 2008.
Download Program Brochure as pdf:
Download InnovationWell-BM08-Final1.pdf
Contact:
Program: Dr. Barry Hardy, InnovationWell Community of Practice, Douglas Connect. Tel: +41 61 851 0170. barry.hardy -[at]- douglasconnect.com
Registration Enquiries: Nicki Douglas, Douglas Connect, Baermeggenweg 14, 4314 Zeiningen, Switzerland. Tel: +41 61 851 0461. InnovationWell -[at]- douglasconnect.com or please visit:
InnovationWell meeting Computational Biology Translational Medicine Systems Biology ADME Predictive ADME Predictive Toxicology Innovative Medicines Community of Practice workshop conference management executive Bryn Mawr Philadelphia Critical Path biomarkers metabolomics toxicology personalised medicine KM Life Sciences Pharma Drug Discovery Drug Safety Research and Development Drug Development Healthcare Innovation Knowledge Management events
SYNERGY, a
new 3 year European-funded Seventh Framework Research Project which commenced on the
1 February 2008, will research the knowledge sharing and collaboration support needs
of stakeholders working collaboratively both internally within organisations,
and within partnerships and new virtual network and business models. The project offers end user organisations an
opportunity to participate in this leading edge research to address their
unique requirements, to undergo a knowledge assessment of their collaboration
needs, and the potential to pilot and test utility-based services developed
during the project.
Swiss-based
Douglas Connect will lead the SYNERGY workpackage on knowledge assessment,
piloting and testing activities of application cases within industry and
business contexts. To provide an opportunity for organisations to learn more
about the initiative and the potential benefits of participation to them, Douglas
Connect will hold a launch and networking event and Knowledge Café at the
Radisson SAS Hotel in Basel, March 6 starting at 15.00. If interested
in attending please contact Nicki Douglas of Douglas Connect, (Email:
Nicki.Douglas –(at)- douglasconnect.com; Tel: +41 61 851 0461) to request a
guest pass.
Following short presentations to inform, the event will feature peer-to-peer
based Knowledge Café discussions on SYNERGY which will be facilitated by:
Prof. Keith Popplewell, Jaguar
Cars Professor of Engineering Manufacture and Management, Coventry University,
UK
Dr. Barry Hardy, Founder, InnovationWell & Knowledge Assessment Leader,
Douglas Connect
Dr. Nenad Stojanovic, FZI Competence Center for Business
Software, Forschungszentrum Informatik an der Universität Karlsruhe, Germany
Dr. Asha
Nagesser, Managing Director, INSIDEAN GmbH
Richard
Zbinden, CEO, Software for Corporate Leaders LLC
A more detailed agenda and project overview is provided in the continuation below.
SYNERGY, a new 3 year European-funded Seventh Framework Research Project commencing on the 1 February 2008, will research the knowledge sharing and collaboration support needs of stakeholders working collaboratively both internally within organisations, and within partnerships and new virtual network and business models. The project offers end user organisations an opportunity to participate in this leading edge research to address their unique requirements, to undergo a knowledge assessment of their collaboration needs, and the potential to pilot and test utility-based services developed during the project. A summary of the project extracted from the formal technical proposal is provided below. (in continuation text)
Continue reading "Knowledge-oriented Collaboration: SYNERGY research project summary " »
We are holding a Knowledge Cafe and networking event at the Merian Hotel, Basel, Switzerland 17.00-20.00, Wednesday 23 April 2008, on the topic of Knowledge & Collaboration.
We will additionally extend the use of supporting the face-to-face cafe conversations with the virtual collaboration tool of a wiki as I used at the Autumn 2007 InnovationWell meeting at Bryn Mawr. (more information on that in a later post)
The Café discussions will be peer-to-peer based and will be co-moderated by:
Beat Knechtli, Director and CKO, PricewaterhouseCoopers
Pavel Kraus, President, Swiss Knowledge Management Forum and Senior Partner, aht'intermediation
Douglas Weidner, President, International Knowledge Management Institute
Barry Hardy, Founder and Director, InnovationWell & Douglas Connect
Chris Pallaris, ISN Chief Editor, Swiss Federal Institute of Technology (ETH Zurich)
Hannes Gassert, CTO, Liip
Nicolette Liller, Microsoft
Asha Nagesser, Managing Director, INSIDEAN
Marco Bettoni, Director of Research & Consulting, Swiss Distance University of Applied Sciences (FFHS)
Richard Zbinden, CEO, Software for Corporate Leaders
The following Guest Seminar will be presented:
17.00 Process-Oriented Knowledge Management
Michael Wyrsch, Vice-President & Leader of the Knowledge Management Competence Center Switzerland, Credit-Suisse
During the Café starting at 18.00, table discussions will include the following Knowledge & Collaboration sub-topics:
Knowledge Sharing, Innovation Networks, Leadership Support, Organisational Complexity & Context, Productivity & Teams, Group Decision-Making, Collaboration Patterns & Roles, Social Networks and Web 2.0, Culture & International Collaboration, and Cooperative Sustainable Development.
The Cafe is free to attend. Light refreshments will be provided. If interested in attending please contact Nicki Douglas (Tel: +41 61 851 0461. Email: Nicki.Douglas –(at)- douglasconnect.com) to reserve a guest place.
The event is co-organised by Douglas Connect, the International Knowledge Management Institute, the Swiss Knowledge Management Forum (SKMF), and the Gurteen Knowledge Community.
Knowledge & Leadership
In 2007 the Basel Knowledge Café focused on *Knowledge & Leadership* whose results formed the basis for an article series being published in KM Review:
B. Hardy; Linking Trust, Change, Leadership & Innovation – Ingredients of a Knowledge Leadership Support Framework; KM Review, Nov/Dec 2007, Vol 10, Issue 5, pp 18-23.
B. Hardy; Collaboration, Culture, and Technology – Contributions to Confidence in Leadership Support; KM Review, Jan/Feb 2008, Vol 10, Issue 6, pp 18-23.
A short summary with photos is posted on the The Ferryman Blog at http://barryhardy.blogs.com/theferryman/2007/06/knowledge_and_l.html
The Café also contributed significantly to the formation of the KLeaders practice and interest group, which has since been working together on developing the ideas of the KLeaders Leadership Practice and Support Framework, and which is currently collaborating on research and network proposals. If you are interested in this research and innovation activity, please contact Dr. Barry Hardy (barry.hardy –(at)- douglasconnect.com, +41 61 851 0170) to discuss your needs or contributions.
Knowledge Collaboration Leadership Knowledge Cafe Douglas Connect KM Institute KM Institute Switzerland meeting workshop training management executive CKM KM Knowledge Management Knowledge Management Training Management Training Basel Innovation Switzerland events
We are running the Certified Knowledge Manager training again in Basel this April. We had an excellent class there last year with many interactions and conversations both in the class and outside on the terrace, in an evening Knowledge Cafe on Knowledge and Leadership (which produced two articles currently being published in KM Review, Nov/Dec 07 and Jan/Feb 08 issues) and on the Knowledge Ferry on the Rhine (which along with Herman Hesse inspired the name of this Blog!) I posted some photos at http://innovationwell.net/COMTY_ckmphotos This year's Cafe will focus on Knowledge and Collaboration. More Information and links below!
Barry
On the morning
of 16 October 2007 as part of our InnovationWell workshop on Information,
Communications, and Knowledge Management Support Systems for R&D (Bryn Mawr College, Philadelphia) we will hold an emerging technologies session featuring the presentation and
discussion of a range of interesting software solutions.
(Please
follow continuation to read)
Continue reading "Emerging ICT Technologies for R&D Support" »
Knowledge Management (KM) has from the start been a major theme of our InnovationWell community activities. Knowledge Management in R&D was the topic of our very first InnovationWell conference held at the end of 2003, progressed in 2004 by the theme of Integrating Knowledge in the Life Science Product Life Cycle, to Drug Safety Knowledge Management and Knowledge-based Innovation in 2005, and to Critical Path and Translational Medicine applications in 2006. More recently we have addressed additional critical knowledge management support areas of culture, collaboration, leadership, trust, innovation etc. In these meeting sessions I have enjoyed both excellent dialogues and meeting many interesting, competent, thoughtful and inspiring people. As we now move into becoming a community of research in addition to a community of practice, these conversations are having a significant influence on the research proposals and projects we are pursuing, and I am very much looking forward to the launch of our initial related collaborative research projects starting in 2008.
It is interesting to note from the Economist survey “Foresight 2020: Examining the Economic, Industry, and Corporate Trends of the Future” that healthcare industry executives singled out knowledge management as the highest priority area for productivity gains in the next 15 years. Such recognition is also reflected in the key role knowledge management plays in the Critical Path Initiative and that it is one of the key 4 pillars of the Innovative Medicines Initiative launching in 2008.
Next month at Bryn Mawr (15-16 October) we return to the topic of KM in R&D by taking a look at existing ICT solutions supporting R&D activities including the increasing deployment of Collaborative electronic Research & Development (CeR&D) and Electronic Laboratory Notebook (ELN) systems. We will additionally explore the emerging roles and impact of approaches emerging from semantic web research, social software, web services and utility computing and Web 2.0/3.0 that are complimentary with structured IT systems to enable increased productivity and innovation success within the context of the ever increasing importance of collaboration within and between organisations working in increasingly networked global research initiatives and projects. Cross-disciplinary thinking from fields such as organisational development and culture, cognitive science and innovation management will I maintain play key influencing roles on future integrating architectures supporting knowledge management, transfer and sharing to enable the hoped-for productivity gains of executives.
The workshop at Bryn Mawr will have a strong emphasis on peer-to-peer discussions with each workshop session involving a facilitated Knowledge Café discussion. On Monday evening we will have a Knowledge Dinner with good food and conversation menus at the Alumni House, whereas on Tuesday evening we will have a poster session, drinks reception and buffet dinner in Thomas Great Hall.
For Poster Presentations, you can present as a traditional poster or setup a computer-based presentation of software for discussion. Wireless and Internet connectivity are available. Abstracts ca. 300-500 words should be sent to me.
We will discuss and share experiences with current information and communications technology (ICT) supporting R&D, to discuss current requirements and short term needs with electronic laboratory notebook (ELN) systems, collaboration support and knowledge tools supporting R&D, and to create a shared vision and roadmap for next generation knowledge management (KM) support systems. A wiki will be opened prior to the workshop to commence group documentation of supporting materials and to help to populate the workshop program with introductory materials, suggestions, ideas and experiences. The wiki will continue to be available after the workshop for supporting continuing interactions in 2008.
Presentations to seed Discussions
Dimitris K. Agrafiotis, Vice President of
Informatics, Johnson & Johnson Pharmaceutical
Research & Development, LLC; The ABCD ELN:
Towards a Fully Integrated Discovery
Enterprise
Frank Guerino, CEO, TraverseIT;
Semantic-based Frameworks for Enterprise
Content Management
Carl Elkin, Principal Scientist,
Schering-Plough; Building Knowledge
Infrastructure: A Bottom-up Wiki in a Large
Company
David Gilmour, CEO, Tacit; Peer-to-Peer
Knowledge Sharing - Implications for
Enterprise Knowledge Management
Alex Heiphetz, CEO, Delta L Training;
Training Simulations and Metrics in Second
Life
Marisol Wesson, CEO, TMS; Enterprise
Knowledge Portals and Application Integration
for supporting Collaboration
Richard Lysakowski, President, CENSA;
Collaborative eR&D - Vision and Strategy to
Product Realities
Jeff Spitzner, CSO, Rescentris; Research
Knowledge Management for the Post-ELN Era:
Envisioning a Multi-Scale 'Scientist's
Desktop' with Unified Information Services,
Management and Collaboration
Gladys Range, Consulting Engineer; GVR
Systems Automation, Semantic Knowledge
Infrastructures and Services for R&D
Program Brochure: http://barryhardy.blogs.com/theferryman/files/KMWorkshopBrynMawr07web2.PDF
More Information at: http://www.innovationwell.net/COMTY_kmworkshopbrynmawr07
eCheminfo InnovationWellinformatics IT KM ICT bioinformatics software Computer Science Software Engineering Software Design Software Development Virtual Environment Virtual Organisation Virtual Worlds Virtual Work Virtual Teams Virtual Laboratory Semantic Web Social Software Enterprise Software Enterprise Systems Enterprise Knowledge Information Systems Information Science Information Technology Chemistry Biology ELN Electronic Lab Notebook Lab Notebook Electronic Laboratory Notebook LIMS R&D pharmaceutical pharma meeting workshop training Philadelphia Knowledge Management innovation collaboration Research Pharma Drug Discovery Research and Development Drug Development Healthcare events
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